What is Fludara Oral

This medicine is an anti-cancer drug approved to treat a form of leukaemia known as B-cell chronic lymphocytic leukaemia (B-CLL). This is a cancer of a type of white blood cells called lymphocytes.

Buy  Fludara online

What is Fludara Oral Patients with B-CLL have too many abnormal white blood cells (lymphocytes) and lymph nodes start to grow in various parts of the body. The abnormal white blood cells cannot carry out their normal disease fighting functions, and may push aside healthy blood cells. This can result in infections, a decreased number of red blood cells (anaemia), bruising and/or bleeding.

Fludara is a medication that stops the growth of new cancer cells. All cells of the body produce new cells like themselves by dividing. To do this, the cells’ genetic material (DNA) must be copied and reproduced. is taken up by the cancer cells and hinders the production of new DNA.

Ask your doctor if you have any questions about why this medicine has been prescribed for you.

There is not enough information to recommend the use of this medicine for children.

Before you take Fludara

When you must not be given it

Do not have any if you have an allergy to:

  • any medicine containing fludarabine
  • any of the ingredients listed at the end of this leaflet.

Some of the symptoms of an allergic reaction may include:

  • shortness of breath
  • wheezing or difficulty breathing
  • swelling of the face, lips, tongue or other parts of the body
  • rash, itching or hives on the skin.

Do not have Fludara if you:

  • are pregnant
  • are breast-feeding
  • your red blood cell count is low because of a type of anaemia (haemolytic anaemia)
  • have severe kidney problems.

Do not take this medicine if you are pregnant. It may affect your developing baby if you take it during pregnancy.

Do not breast-feed if you are taking this medicine.

It is possible that your baby may be affected if you breast-feed.

If you are not sure whether you should start taking this medicine, talk to your doctor.

Before you take it

Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes.

Tell your doctor if you have or have had any of the following medical conditions:

  • low protein in the blood (hypoalbuminaemia). Your doctor will have told you if you have this.
  • you fell very unwell, have unusual bruising, more bleeding than usual after injury, or if you seem to be catching a lot of infections
  • poor kidney function
  • enlarged liver or spleen, reduced liver function
  • skin cancer.

If you have or have had skin cancer it may worsen or flare up again while you take Fludara or afterwards.

Tell your doctor if you are over 75 years of age. Your doctor will administer Fludara to you with caution and monitor your closely.

Tell your doctor if the person is below 18 years of age. It is not recommended to give this medicine to a child under the age of 18 years.

Tell your doctor if you are pregnant or plan to become a parent. Men and women who may still be fertile must use a reliable form of contraception during treatment and for at least 6 months after stopping therapy. It is not known whether Fludara decreases your fertility. Your doctor can discuss with you the risks and benefits involved.

If you have not told your doctor about any of the above, tell him/her before you start taking .

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop.

Some medicines and Fludara may interfere with each other. These include:

  • pentostatin (deoxycoformycin) also used to treat B-CLL. Taking these two drugs together can lead severe lung problems.
  • cytarabine (Ara-C) used to treat chronic lymphatic leukaemia
  • dipyridamole, used to prevent excessive blood clotting, or other similar drugs
  • live viral vaccines. It is recommended that patients do not receive live viral vaccines during and after treatment with .

These medicines may be affected by or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines.

Your doctor may have more information on medicines to be careful with or avoid while taking this medicine.

How to take Fludara Oral

Fludara should be administered under the supervision of a qualified physician experienced in the use of cancer therapy. The dose you should take depends on your body surface area. This is measured in square metres (m2), and is worked out by the doctor from your height and weight.

Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet.

If you do not understand the instructions on the box/bottle, ask your doctor or pharmacist for help.

How much to take

The recommended dose is 40mg per square metre of body surface area, once a day. The exact number of tablets you should take is calculated by your doctor. The usual dose is between 3 to 10 tablets once a day.

How to take it

Swallow the tablets whole with a full glass of water. Do not chew or break the tablets.

When to take it

Take the tablets the same time every day.

Fludara can be taken either on an empty stomach or together with food.

How long to take it

Take the dose worked out by your doctor once a day for 5 consecutive days.

The 5-day course of treatment will be repeated every 28 days until your doctor has decided that the best effect has been achieved (usually after 6 courses). Your doctor may adjust the dose and number of treatment days.

Attend all of your doctor’s appointments so that your progress can be checked. You will have blood tests after every treatment course. Your individual dose will be carefully adjusted according to the number of your blood cells and your response to the therapy.

Continue taking your medicine for as long as your doctor tells you. This medicine helps to control your condition, but does not cure it. It is important to keep taking your medicine even if you feel better.

If you forget to take it

Talk to your doctor as soon as possible if you think you may have missed a dose or vomit after tablet taking. Do not take a double dose to make up for the forgotten tablets. This may increase the chance of you getting an unwanted side effect.

If you have trouble remembering to take your medicine, ask your pharmacist for some hints.

If you take too much (overdose)

Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26) or New Zealand National Poisons Information Centre (telephone 0800 764 766, or 0800 POISON) for advice, or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much Fludara. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

Overdose can cause delayed blindness, coma and even death.

While you are using Fludara

Things you must do

If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Fludara.

Tell any other doctors, dentists, and pharmacists who treat you that you are taking this medicine.

If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine. It may affect other medicines used during surgery.

If you notice anything new or unusual on your skin, suggestive of skin cancer, tell your doctor.

  • If you have or have had skin cancer it may worsen or flare up again while you take Fludara or afterwards. You may also develop skin cancer during or after therapy as it reduces your body’s defence mechanisms.

If you are a fertile male or female of childbearing potential, ensure that you use a reliable form of birth control during treatment and for at least 6 months after treatment. If you do become pregnant while taking this medicine, tell your doctor immediately. The effects of this medicine on reproduction are unknown.

If you are about to have any blood tests, tell your doctor that you are taking this medicine. It may interfere with the results of some tests.

If you need a blood transfusion, tell your doctor. Your doctor will ensure that you receive blood that has been treated by irradiation. There have been severe complications and even death, from transfusion of non-irradiated blood.

Keep all of your doctor’s appointments so that your progress can be checked. Your doctor may do some tests from time to time to make sure the medicine is working and to prevent unwanted side effects.

Check with your doctor before receiving any vaccinations. Live vaccinations should be avoided during and after treatment with .

Things you must not do

Do not take Fludara to treat any other complaints unless your doctor tells you to.

Do not give your medicine to anyone else, even if they have the same condition as you.

Do not stop taking your medicine or change the dosage without checking with your doctor. If you stop taking it suddenly, your condition may worsen.

Things to be careful of

Be careful driving or operating machinery until you know how Fludara affects you. This medicine may cause fatigue, weakness, visual disturbances, confusion, agitation and rare seizures in some people. If you have any of these symptoms, do not drive, operate machinery or do anything else that could be dangerous.

Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking FLUDARA. This medicine helps most people with B-cell chronic lymphocytic leukaemia (B-CLL), but it may have unwanted side effects. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects.

Do not be alarmed by the following list of side effects.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor or pharmacist if you notice any of the following and they worry you:

  • infections with symptoms of fever, severe chills, sore throat or mouth ulcers
  • symptoms of anaemia such as tiredness, headaches, being short of breath when exercising, dizziness and looking pale
  • some bruising
  • loss of appetite leading to weight loss
  • numbness or weakness in the arms and legs
  • cough
  • nausea, vomiting, diarrhoea
  • sore mouth or gums
  • mouth ulcers
  • skin rash
  • fever
  • tiredness
  • chills
  • weakness and/or generally feeling unwell
  • swelling due to excessive fluid retention.

The above list includes the more common side effects of your medicine. They are often mild or moderate problems that are short-lived and diminish during the course of treatment. However, if you believe the side effect is of a more severe nature, tell your doctor as soon as possible.

Tell your doctor as soon as possible of you notice any of the following:

  • severe bruising
  • more bleeding than usual after injury
  • you seem to be catching a lot of infections
  • anything new or unusual on your skin such as mole, freckle or sore; a spot, mole or freckle that has changed in colour, shape or size
  • symptoms of pneumonia such as fever, chills, shortness of breath, cough and phlegm that may be blood stained
  • visual disturbances.

The above list includes serious side effects that may require medical attention.

If any of the following happen, tell your doctor immediately or go to Accident and Emergency at your nearest hospital:

  • sudden signs of allergy such as rash, itching or hives on the skin, swelling of the face, lips, tongue or other parts of the body, shortness of breath, wheezing or trouble breathing
  • red to brownish urine, rash or any blisters on your skin
  • vomiting blood or material that looks like coffee grounds, bleeding from the back passage, black sticky bowel motions (stools) or bloody diarrhoea
  • seizures, unconsciousness
  • sudden dimming or loss of vision
  • symptoms of heart disease such as shortness of breath, and swelling of the feet or legs due to fluid build-up
  • abnormal heartbeat (irregular, fast or slow)
  • difficulty breathing, shortness of breath, severe cough, sharp chest pains
  • signs of tumour lysis syndrome such as pain in one side of the body under the rib cage, little or no urine, drowsiness, nausea, vomiting, breathlessness, irregular heart beat, loss of memory, loss of consciousness
  • signs of Stevens-Johnson syndrome, such as skin and/or mucous membrane reaction with redness, inflammation, blistering and erosion
  • signs of toxic epidermal necrolysis which starts with painful red areas, then large blisters and ends with peeling of layers of skin. This is accompanied by fever and chills, aching muscles and generally feeling unwell.
  • Neurological disorders manifested by headache, feeling sick (nausea) and vomiting, seizures, visual disturbances including vision loss, changes in mental status (thinking abnormal, confusion, altered consciousness), and occasionally neuromuscular disorders manifested by muscle weakness in your limbs (including irreversible partial or complete paralysis) (symptoms of leukoencephalopathy, acute toxic leukoencephalopathy or posterior reversible leukoencephalopathy syndrome (RPLS))
  • bleeding in the lungs
  • inflammation of the bladder, which can cause pain when passing urine, and can lead to blood in the urine (haemorrhagic cystitis).

The above list includes very serious side effects. You may need medical attention or hospitalisation. These side effects are usually uncommon or rare.

Tell your doctor or pharmacist if you notice anything that is making you feel unwell.

Other side effects not listed above may also occur in some people.

Keep all doctor’s appointments do your progress can be checked. Some side effects (for example, blood disorders) can only be found when your doctor does tests on a regular basis.

After using Fludara Oral

Storage

Keep your tablets in the pack until it is time to take them. If you take the tablets out of the pack they may not keep well.

Keep your tablets in a cool dry place where the temperature stays below 25°C.

Do not store Fludara or any other medicine in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres about the ground is a good place to store medicines.

Disposal

If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over.

Product description

What it looks like

Fludara Oral film-coated tablets are salmon coloured oval shaped with “LN” indented in a regular hexagon on one side. The tablets are packaged in blisters of 5 tablets and three or four blisters are packed in child resistant containers.

Ingredients

Each Fludara Oral tablet contains 10mg of fludarabine phosphate.

It also contains:

  • microcrystalline cellulose
  • lactose
  • silica-colloidal anhydrous
  • croscarmellose sodium
  • magnesium stearate
  • hypromellose
  • purified talc
  • titanium dioxide
  • iron oxide red CI 77491
  • iron oxide yellow CI 77492

Sponsor

In Australia this product is distributed by: 
Genzyme Australasia Pty Ltd
Level 1, Building C
12-24 Talavera Road
North Ryde
NSW 2113
Toll Free Number (medical information): 1800 818 806
Email: medinfo.australia@sanofi.com

In New Zealand this product is distributed by: 
Sanofi-Aventis New Zealand Limited
Level 8, James and Wells Tower
56 Cawley Street, Ellerslie,
Auckland
New Zealand
Toll Free Number (medical information): 0800 283 684 (option 2)

Australian Registration Number: 
AUST R 81998

Date of preparation: 24 November 2014Delivery info

Please note that Public Holidays will add on extra delivery time for orders

SuperPharmacy orders will be packaged in plain, impervious packaging that is unmarked for security and privacy reasons. Orders will be dispatched as soon as possible once payment is received. 

We will dispatch most orders within business day from Monday to Friday, assuming all items are in stock. All other orders will be dispatched as quickly as possible thereafter.

For Orders containing prescription items please see the prescription processing procedure.

Australia Wide shipment details

We offer Standard Shipping for $4.95** with approximately 4-8 business days of transit time based upon your location within Australia.*

We also offer an Express Delivery Service for $10.95** with approximately 1-3 business days of transit time based upon your location within Australia.*

All Australian orders $99 or more in value will qualify for FREE Standard Shipping or Express Delivery at $7.95

Any orders that contain an item that requires Cold-Chain Shipping will incur a $10.95 Express Delivery Fee. This will overwrite any other thresholds.

Any orders over 5kgs will have our Online Team be in contact with further information regarding shipping.

All orders of Prescription items will receive FREE Delivery regardless of order value.

*These estimations are based upon transit time once dispatched from our locations. Please note our couriers do not operate on weekends and public holidays.

**These delivery costs do not represent orders that we consider ‘Bulk Orders’.  Bulk Orders will have our Online Team be in touch in order to discuss appropriate shipping costs. For clarification on what we classify as a ‘Bulk Order’, refer to our terms and conditions or give us a call.

Sending a Prescription to SuperPharmacy.

When you purchase prescription medication online with SuperPharmacy, we need a valid script in our possession before we can dispatch your medications to you. 

For Electronic Prescriptions, it is now as easy as sending your Token to epharmacist@superpharmacy.com.au.

For Paper Prescriptions, we still require the physical paperwork in our possession, so they can only be processed once we physically receive your prescription paperwork. Prescription product orders will be dispensed and dispatched on the business day the prescription or valid repeat authorisation is received at the SUPERPHARMACY registered premises. Please send your prescription paperwork to the appropriate store

NSW, ACT and TAS:  SUPERPHARMACY PO Box 1877 Hornsby Westfield 1635

QLD or NT: Superpharmacy 187 Days Road Grange Qld 4051

SA: Superpharmacy 41 Hindley street Adelaide, SA 5000

VIC: Superpharmacy 92 Lygon Street East Brunswick VIC 3057

WA: Superpharmacy 259 Walcott St, North Perth WA 6006

Can I send a photo of my Script?

A photo is only valid for Electronic Prescriptions. For traditional Paper Prescriptions, we will need you to post the script to us as highlighted above.

Postage and handling for international orders

We do not currently deliver outside of Australia Returns & exchanges

How Do Returns & Refunds Work?


We are happy to offer refunds or exchanges on any item (excluding restricted items*) that you have purchased from us.

Important: You are not entitled to, or guaranteed, a refund for Change of Mind returns. They will be processed at our discretion. We reserve the right to charge a restocking fee for Change of Mind returns.
You will be responsible for the cost of shipping to return goods to us unless we specify that we will cover the cost.

Note: Legislation prohibits us from accepting Prescription Items for refund or exchange.

All we ask is that you follow the below to qualify:

  1. Check your products as soon as you receive delivery. Ensure the correct items have been sent, and nothing is damaged or in an unusable condition.
     
  2. Contact us within 30 days from your order date (7 days for damaged/incorrect items).
     

How We Handle Them:
 

Change of Mind

  • If you’ve had a change of mind about an item you have ordered, we’ll need to receive it back to us unopened and unused, in the original packaging.
     

Faulty Item

  • If the item you have received is faulty, please contact us with a detailed description of the product fault, alongside a photo if possible.

Allergic Reaction

  • In the rare instance you’ve had an allergic reaction to a product, please discontinue use of the product immediately. We may reach out for further information on the reaction.

Allergy returns must be less than 20% used upon arrival back to us.
 

Incorrect / Damaged Items

  • If you have received an item that isn’t what you ordered, or it arrived damaged, please take a photo and contact us within 7 days of delivery. 

Please don’t dispose of the item without informing us.

The Process:

  1. Contact Us
    • To start a return, please send your request to cuperpharmacy.com.au. Make sure we have received & acknowledged your request before you send the item back to us.
       
  2. Instructions
    • A Customer Service Team Member will then review your request, and be in touch with some further information. Should your request be approved, they will supply a return address for you to post the item back to us, and instructions on how to do so.
       
  3. Drop Off At Your Post Office
    • Once you have received the returns address and packaged and labelled your box as instructed, all you need to do is drop off the parcel at your local Post Office. From there, they will take care of getting the parcel back to us.
       
  4. We Receive Your Return
    • It can take anywhere from an estimated 1-10 business days for us to receive your return parcel back to us (depending on location). We check for any returns daily and will process the refund/exchange within 2 business days after receiving the item back to us. We will make sure the entire process is communicated to you once we receive the item back.

Am I Eligible For Free Return Shipping?

If you qualify for free return shipping, our Customer Service Team will make this clear to you in your request. Unfortunately, we are not able to cover return postage fees on all return types.

What Items Are Restricted For Returns*?

We will not accept Change of Mind Returns for the following items:

  • Baby Formula
  • Prescription Medicine
  • Perfumes & Colognes
  • Bulk / Special Orders

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